Amphetamines are a family of synthetic stimulants that increase alertness, energy and focus by raising levels of dopamine and noradrenaline in the brain. The two members that matter most for property contamination are amphetamine itself and methamphetamine, which is amphetamine with one additional methyl group on the nitrogen atom.
Illicit amphetamine is most often sold as a powder, commonly called speed, and is usually snorted, swallowed or injected. Methamphetamine, particularly crystal methamphetamine, is more potent, more widely used in Australia and is usually smoked. Because smoking deposits so much more residue on surfaces than other routes, methamphetamine dominates most contaminated property results.
Amphetamine also has a legitimate medical life. Dexamphetamine and lisdexamfetamine are prescribed in Australia for conditions including ADHD. That is one reason a low amphetamine result on its own must always be read in context, and why speciation is so valuable. A result that simply says amphetamines were present, without separating the compounds, loses most of the information that matters.
In the body, a proportion of methamphetamine is converted to amphetamine. On surfaces, the relative amounts of the two compounds, and how they change from room to room, can reflect how the drug was used, how it was made and how long ago the residue was deposited.